Your Saturn in Scorpio is the karmic, or teacher planet. Since it's in the 4th house of family, perhaps there is some lesson you are supposed to be learning from these relationships and estrangements. Especially the ones of your sister and daughters. Venus in Scorpio is passionate, but maybe you are turning your back on these people too soon without trying to work things out? It's a Scorpio trait to just walk away from people if you can't get along, but having done it myself, I find it's wiser to leave the door open.
It seems odd all these people would mistreat you for no reason, and I don't have a whole chart to interpret. It is karmic. If you want to break the cycle, you have to be the one to reach out and talk about the issues. And I don't know if you are ready to do this. You sound like you feel victimized, and maybe you were. There's really not a way I can answer this so well.
Scorpio Moon people are loyal and passionate. I see too many people using Scorpio Moons and Suns as reasons to scapegoat other people when that's not the real issue. Maybe some soul searching and real attempt to try to get along without blaming astrology for it is a good start. Good luck.