You have some very sympathetic planets in zodiac signs here. Cancer rising means you seem nurturing and kind. Taurus Moon is a kind emotional outlook, but a sensible one, so you can use that sense to be sure nobody takes advantage of you. Venus in Pisces is so romantic, and you will do anything for loved ones. The Aquarius Sun is more detached, so that's an area and tool you could utilize more.
Aquarius and Taurus are fixed signs, so you are stubborn and persistent. You are a bit of a nonconformist and know who you are. Cancer rising people are normally outgoing and ambitious. So I don't know what is causing the lack of confidence. It could be you are hanging out with the wrong people because these planetary positions shouldn't make you feel unsure of yourself. Of course, there's a lot more to astrology then what zodiac signs your planets are in.
In astrology and life, we have Free Will. If the people in your life are toxic, get away from them. If it's at work, or a place you must be around them, interact with them as little as possible. You are creative, and being Aquarius, may want to have a business of your own. Both Aquarius and Cancer people aren't really the 9 to 5 office type. Think about what you are good at, or maybe consider taking some courses, or getting a new job. Then you could meet new people. Maybe the job is so wrong for you, it's bringing you close to people too different to you. So you can do inner work, figure out what another type of work you may like more. If you meet someone and think they will be a drain on you, don't get to know them better, don't call them back. If it's a love relationship, and after a short time, it seems to be going in a direction you feel is toxic, break up. This is all in your power. Do something about it. You can do it! Let me know how it goes. Take baby steps. Make a list of jobs that may interest you. Make a decision if one toxic person really needs to be in your life. Get rid of them if possible, or if they are family, don't see them if you don't have you. It's up to you to take control of your life.